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Publications of Professor Mark R. Biscoe:

32. Ralph, Glenn; Reghuvaran Santha, Asha; Agyemang, Nana B.; Ma, Xinghua; Zuschlag, Daniel W.; Murray, Benjamin; Biscoe, Mark R. "Cu-Controlled Enantiodivergent Pd-Catalyzed Stille Cross-Coupling Reactions." 10.26434/chemrxiv-2025-mj57m.

31. Biscoe, Mark R.; Cornella, Josep; Kalyani, Dipannita; Neufeldt, Sharon. "From Established to Emerging: Evolution of Cross-Coupling Reactions." J. Org. Chem. 2024, 89, 16065–16069.

30. Binayeva, Meruyert; Ma, Xinghua; Ghaemimohammadi, Pejman; Biscoe, Mark R.* "A General Approach to Stereospecific Pd-Catalyzed Cross-Coupling Reactions of Benzylic Stereocenters." Chem. Sci. 2023, 14, 14124–14130.

29. Zhao, Haoran; Jose, Anju Treesa; Asany, Alisajat; Khan, Shahrukh M.; Biscoe, Mark R.* "Pd-Catalyzed Arylation of Secondary a-Alkoxytricyclohexylstannanes." Org. Lett. 2022, 24, 8714–8718.

28. Murray, Benjamin; Zhao, Shibin; Aramini, James M.; Wang, Hsin; Biscoe, Mark R.* "The Stereochemical Course of Pd-Catalyzed Suzuki Reactions Using Primary Alkyltrifluoroborate Nucleophiles." ACS Catal. 2021, 11, 2504-2510.

27. Ma, Xinghua; Murray, Benjamin; Biscoe, Mark R.* "Stereoselectivity in Pd-Catalyzed Cross-Coupling Reactions of Enantioenriched Nucleophiles." Nat. Rev. Chem. 2020, 4, 584-599.

26. Liu, Min Ting; Na, Mihwa; Li, Yadi; Biscoe, Mark R.; Ryan, Kevin.* "Conformational Sensing by a Mammalian Olfactory Receptor." Chem. Eur. J. 2020, 26, 11462-11469.

25. Ma, Xinghua; Zhao, Haoran; Binaveya, Meruyert; Ralph, Glenn; Diane, Mohamed; Zhao, Shibin; Wang, Chao-Yuan; Biscoe, Mark R.* "A General Approach to Stereospecific Cross-Coupling Reactions of Nitrogen-Containing Stereocenters." Chem 2020, 6, 781-791.

24. Ralph, Glenn; Biscoe, Mark R.* "Preparation of Enantioenriched Alkylcarbastannatranes via Nucleophilic Inversion of Alkyl Mesylates for Use in Stereospecific Cross-Coupling Reactions." Organometallics 2019, 38, 3912-3915.

23. Zhao, Shibin; Gensch, Tobias; Murray, Benjamin; Niemeyer, Zachary L.; Sigman, Matthew S.*; Biscoe, Mark R.* "Enantiodivergent Pd-Catalyzed C–C Bond Formation Enabled through Ligand Parameterization." Science 2018, 362, 670-674.

22. Ma, Xinghua; Diane, Mohamed; Ralph, Glenn; Chen, Christine; Biscoe, Mark R.* "Stereospecific Electrophilic Fluorination of Alkylcarbastannatrane Reagents." Angew. Chem. Int. Ed. 2017, 56, 12663-12667.

21. Wang, Chao-Yuan; Ralph, Glenn; Derosa, Joseph; Biscoe, Mark R.* "Stereospecific Pd-Catalyzed Acylation of Alkylcarbastannatrane Reagents: A General Alternative to Asymmetric Enolate Reactions." Angew. Chem. Int. Ed. 2017, 56, 856-860. [Highlighted in:  Synfacts 2017, 258]

20. Wang, Chao-Yuan; Derosa, Joseph; Biscoe, Mark R.* "The Use of Stable, Optically Active Organometallic Nucleophiles in Cross-Coupling Reactions: A New Approach to Asymmetric Synthesis." Chem. Sci. 2015, 6, 5105-5113.

19. Li, Ling; Zhao, Shibin; Joshi-Pangu, Amruta; Diane, Mohamed; Biscoe, Mark R.* "Stereospecific Pd-Catalyzed Cross-Coupling Reactions of Secondary Alkylboron Nucleophiles and Aryl Chlorides." J. Am. Chem. Soc. 2014, 136, 14027-14030.

18. Li, Ling; Wang, Chao-Yuan; Huang, Rongcai; Biscoe, Mark R.* "Stereoretentive Pd-Catalyzed Stille Cross-Coupling Reactions of Secondary Alkyl Azastannatranes and Aryl Electrophiles." Nat. Chem. 2013, 5, 607-612. [Highlighted in:  Synfacts 2013, 100]

17. Li, Ling; Biscoe, Mark R.* "Alkylzinc Cross-Coupling Reactions." In Cross-Coupling and Heck-Type Reactions, Vol. 1; Molander, G., Ed.; Georg Thieme Verlag HG: Stuttgart, 2013, pp 795-837.

16. Joshi-Pangu, Amruta; Ma, Xinghua; Diane, Mohammed; Iqbal, Sidra; Kribs, Robert J.; Huang, Richard; Wang, Chao-Yuan; Biscoe, Mark R.* "Palladium-Catalyzed Borylation of Primary Alkyl Bromides." J. Org. Chem. 2012, 77, 6629-6633.

15. Joshi-Pangu, Amruta; Biscoe, Mark R.* "The Use of Teriary Alkyl Nucleophiles in Metal-Catalyzed Cross-Coupling Reactions." Synlett 2012, 23, 1103-1107. [Synpact article: invited review highlighting work in pub. 14]

14. Joshi-Pangu, Amruta; Wang, Chao-Yuan; Biscoe, Mark R.* “Nickel-Catalyzed Kumada Cross-Coupling Reactions of Tertiary Alkylmagnesium Halides and Aryl Bromides/Triflates.” J. Am. Chem. Soc. 2011, 133, 8478-8481. [Highlighted in:  Synfacts 2011, 897]

13. Joshi-Pangu, Amruta; Ganesh, Madhu; Biscoe, Mark R.* “Nickel-Catalyzed Negishi Cross-Coupling Reactions of Secondary Alkylzinc Halides and Aryl Iodides.” Org. Lett. 2011, 13, 1218-1221. [Highlighted in:  Synfacts 2011, 662]

12. Biscoe, Mark R.; Buchwald, Stephen L. “The Selective Monoarylation of Acetate Esters and Aryl Methyl Ketones Using Aryl Chlorides.” Org. Lett. 2009, 11, 1773-1775.

11. Lee, Brian K.; Biscoe, Mark R.; Buchwald, Stephen L. “Simple, Efficient Protocols for the Pd-Catalyzed Cross-Coupling Reaction of Aryl Chlorides and Dimethylamine.” Tetrahedron Lett. 2009, 50, 3672-3674 [50th anniversary special issue].

10. Fors, Brett P.; Watson, Donald A.; Biscoe, Mark R.; Buchwald, Stephen L. “A Highly Active Catalyst for Pd-Catalyzed Amination Reactions:  Cross-Coupling Reactions Using Aryl Mesylates and the Highly Selective Monoarylation of Primary Amines.” J. Am. Chem. Soc. 2008, 130, 13552-13554.

9. Biscoe, Mark R.; Fors, Brett P.; Buchwald, Stephen L. “A New Class of Easily Activated Palladium Precatalysts for Facile C–N Cross-Coupling Reactions and the Low Temperature Oxidative Addition of Aryl Chlorides.” J. Am. Chem. Soc.2008, 130, 6686-6687.  [Featured as Editor’s Choice in:  Science 2008, 320, 850-851]

8. Biscoe, Mark R.; Barder, Timothy E.; Buchwald, Stephen L. “Electronic Effects on the Selectivity of Pd-Catalyzed C–N Bond-Forming Reactions Using Biarylphosphine Ligands: The Competitve Roles of Amine Binding and Acidity.” Angew. Chem. Int. Ed. 2007, 46, 7232-7235.

7. Ikawa, Takashi; Barder, Timothy E.; Biscoe, Mark R.; Buchwald, Stephen L. “Pd-Catalyzed Amidations of Aryl Chlorides Using Monodentate Biaryl Phosphine Ligands:  A Kinetic, Computational, and Synthetic Investigation.” J. Am. Chem. Soc. 2007, 129, 13001-13007.

6. Barder, Timothy E.; Biscoe, Mark R.; Buchwald, Stephen L.  “Structural Insights into Active Catalyst Structures and Oxidative Addition to (Biaryl)phosphine-Palladium Complexes via Density Functional Theory and Experimental Studies.” Organometallics 2007, 26, 2183-2192.

5. Uyeda, Christopher; Biscoe, Mark; Leplae, Paul; Breslow, Ronald. “Hydrophobically-Directed Selective Reduction of Ketones Using Amine Boranes.” Tetrahedron Lett. 2006, 47, 127-130.

4. Biscoe, Mark R.; Breslow, Ronald. “Oxaziridinium Salts as Hydrophobic Epoxidation Reagents: Remarkable Hydrophobically-Directed Selectivity in Olefin Epoxidation.” J. Am. Chem. Soc. 2005, 127, 10812-10813.

3. Biscoe, Mark R.; Uyeda, Christopher; Breslow, Ronald. “Requirements for Selective Hydrophobic Acceleration in the Reduction of Ketones.” Org. Lett. 2004, 6, 4331-4334.

2. Biscoe, Mark R.; Breslow, Ronald. “Hydrophobically-Directed Selective Reduction of Ketones.”  J. Am. Chem. Soc. 2003, 125, 12718-12719.

1. Biscoe, M. R.; Fry, A. J. “Dual Reaction Pathways in the Magnesium-Mediated Synthesis of Aziridines from Benzal Halides and Imines.” Tetrahedron Lett. 2001, 42, 2759-2762.