Dr. Lingyan Shi is leading deep brain imaging research in CCNY鈥檚 Institute for Ultrafast Spectroscopy and Lasers.
The neuroscience community is saluting the creation of a 鈥淕olden Window鈥 for deep brain imaging by researchers at 海角社区 led by biomedical engineer . This is a first for brain imaging, said Shi, a research associate in City College鈥檚 Institute for Ultrafast Spectroscopy and Lasers, and the biology department.
The breakthrough holds promise for the noninvasive study of the brain and breasts in greater detail than possible today.
Working with Distinguished Professor of Physics Robert R. Alfano and Adrian Rodriguez-Contreras, an assistant professor of biology, Shi鈥檚 team proved theoretically and experimentally that deep imaging of the brain is possible using light at wavelength 1600-1880nm (nanometer). This is dubbed the 鈥淕olden Window鈥 for imaging.
In the past, near-infrared (NIR) radiation has been employed using one and two-photon fluorescence imaging at wavelengths 650鈥950 nm for deep brain imaging. This is known as optical window 1.
Shi, who earned a Ph.D. in biomedical engineering from CCNY鈥檚 Grove School of Engineering in 2014, said the current research introduces three new optical windows in the NIR region. And she demonstrates the windows鈥 potential for deeper brain tissue imaging due to the reduction of scattering that causes blurring. Published by the 鈥,鈥 her study sheds light on the development of next generation of microscopy imaging technique, in which the 鈥淕olden Window鈥 may be utilized for high resolution deeper brain imaging.
The next step in the research is in vivo imaging in mice using Golden Window wavelength light.
About 海角社区
Since 1847, 海角社区 has provided low-cost, high-quality education for New Yorkers in a wide variety of disciplines. More than 16,000 students pursue undergraduate and graduate degrees in: the College of Liberal Arts and Sciences; the Bernard and Anne Spitzer School of Architecture; the School of Education; the Grove School of Engineering; the Sophie Davis School of Biomedical Education, and the Colin Powell School for Civic and Global Leadership. U.S. News, Princeton Review and Forbes all rank City College among the best colleges and universities in the United States.